Is Keratoconus genetic in origin?
There is increasing evidence that genetics plays a large part in keratoconus but it is by no means the whole story. Genetic research so far has thrown up many different gene locations and associations with differing medical conditions. The links below are some of the myriad ones out there on the internet. if anyone has any other informaiton that visitors here would find useful - please contact us on admin@cxlclub.org
Articles and links
EYE on Research (includes other information on INTACS and CXL)
Apparent autosomal dominant keratoconus in a large...[Hum Genet. 2008]
Two-Stage Genome-Wide Linkage Scan in Keratoconus Sib Pair Families
Keratoconus: epidemiology, risk factors and diagnosis...[Klin Monatsbl Augenheilkd. 2006]
Videokeratographic anomalies in familial keratoconus...[Ophthalmology. 2004]
FHA - SOD1: a candidate gene for keratoconus - Article Summary
VSX1 gene variants are associated with keratoconus...[J Hum Genet. 2008]
Genetic Epidemiological Study of Keratoconus: Evidence for Major Gene Determination